Reference values for lung function tests: III. Carbon monoxide diffusing capacity (transfer factor)

Reference values for lung function tests. III. Carbon monoxide diffusing capacity (transfer factor).

Carbon monoxide diffusing capacity (DLCO) or transfer factor (TLCO) is a particularly useful test of the appropriateness of gas exchange across the lung alveolocapillary membrane. With the purpose of establishing predictive equations for DLCO using a non-smoking sample of the adult Brazilian population, we prospectively evaluated 100 subjects (50 males and 50 females aged 20 to 80 years), rando...

Single breath carbon monoxide diffusing capacity (transfer factor)

Maximal Diffusing Capacity of the Lung for Carbon Monoxide.

The measurement of co uptake (VCO and DLCO) from alveolar gas is a unique way to noninvasively assess pulmonary vascular function, specifically the functional volume of the pulmonary capillary bed. Proper interpretation of results, however, needs to account for inherent assumptions regarding co distribution and timing procedures. Moreover, reasonable airway mechanics, lung volumes, and patient ...

Importance of appropriately adjusting diffusing capacity of the lung for carbon monoxide and diffusing capacity of the lung for carbon monoxide/alveolar volume ratio for lung volume.

In their report on cardiac sarcoidosis, Smedema et al (July 2005)1 remarkably conclude that patients without cardiac symptoms do not require more sensitive studies to detect heart disease. This report, while of interest, is limited by a patient follow-up that varied widely from 3 to 54 months. Since this study does not well characterize the natural history of asymptomatic cardiac sarcoidosis an...

Official ERS technical standards: Global Lung Function Initiative reference values for the carbon monoxide transfer factor for Caucasians.

There are numerous reference equations available for the single-breath transfer factor of the lung for carbon monoxide (T LCO); however, it is not always clear which reference set should be used in clinical practice. The aim of the study was to develop the Global Lung Function Initiative (GLI) all-age reference values for T LCOData from 19 centres in 14 countries were collected to define T LCO ...